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Cannabis Can Prevent The Effects Of Stress-Related Depression


Marijuana brain stress depressionCourtesy of The Joint Blog

A new study published this week by the National Institute of Health has found that cannabinoids can prevent the effects of stress-induced depression.

For the study – which was conducted at the University of Haifa - researchers used animal models to examine if activation of the body’s cannabinoid receptors (something which cannabis does naturally) can “ameliorate the effects of CMS [chronic mild stress]on emotional learning (ie, conditioned avoidance and extinction), long-term potentiation (LTP) in the hippocampal-accumbens pathway and depression-like symptoms (ie, coping with stress behavior, anhedonia and weight changes).”

Researchers found that cannabinoid receptor activation “prevented the CMS-induced alterations in emotional memory (ie, extinction) and plasticity.”

Researchers concluded that; “The findings suggest that enhancing cannabinoid signaling could represent a novel approach to the treatment of cognitive deficits that accompany stress-related depression.”

This study will be published in print in the journal Neuropsychopharmacology.

Source: TheJointBlog.Com


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Johnny Green


  1. I am so glad that there are some others that feel the same way. I know the state that I’m in it’s still illegal BUT would I rather go back to yelling at my 3 kids all day, biting my hubby’s head off, being to depressed to function, even get out of bed. I had to have someone with me all the time because I couldn’t handle 3 kids,. (Granted I have 2 year old twin boys they are VERY hard to handle at times!) My house was always a mess. Dishes piled up, floor needed swept etc. No I WOULD rather talk to my kids and play with them, and take them places. Tonight we rode on a combine, last night we made muffins. My daughter is excelling in school because I have the patience and understanding to sit down with her and help her do her homework. We joined Girl Scouts so we could have mommy/daughter time. I make sure she knows the difference between right and wrong. I genuinely care. Not that I didn’t before but I actually enjoy all those activities. If it’s illegal to feel that way, then take me to jail.

  2. I’ve been in the same boat. Tried the gamut of antidepressants, but mj is the only thing that has ever worked for me. Three years and counting now, and I haven’t been depressed at all in that time. I used to think about killing myself each and every day. I prefer to love life than to hate it and fuck anyone who says that’s wrong.

  3. Anti-depressants work for very few people. Approved by the FDA with industry-provided research (negative research was not submitted), and abused by psychiatrists and pain doctors, anti-depressants are a joke. I’m so very glad that you were able to stop taking them and switch to cannabis.

    Adults drink alcohol and smoke cigarettes in front of kids all the time, but it will take some time before marijuana gains this kind of public acceptance. (Of course, no more “public acceptance” for cigarette smokers…) People like to get drunk and they like to get baked, but responsible use is not a hard concept. Thanks for being a role model young lady!

  4. Although I do not want anything to happen to Willie Nelson, I think his brain would be a great case-study in life-long cannabis use. How may new areas of the brain were created after a life-long habit? Does his brain have neurons (and stuff) that were created by cannabis and that do amazing things?

  5. So glad you have found a healthier and safer alternative to mad made prescribed poisons Lacey. I know I’m a better Mom and wife when I can sneak off every now and then and do a couple one hits. Depression and stress are a very real killer of relationships and our bodies, marijuana is definitely the cure all. Keep enjoying that 5 P.M. relaxing time :)

  6. I was on anti-depressants for 13 years. In Aug of this year I had enough. I started smoking everyday at 5 pm. Almost 3 months later, WOW. I haven’t felt like this since I started taking anti-depressants. I am able to function again, my house looks awesome, my kids are so very happy, my husband is happy, and my entire family has noticed a difference in me. Now don’t take it all out of proportion when I say I have kids and smoke. I do not get baked nor do I do it near them.

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