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Compounds In Cannabis Found To Reduce Nausea In New Study


digestive disorder marijuana cannabis nauseaCourtesy of The Joint Blog

new study published by the British Journal of Pharmacology and the National Institute of Health has found that THCV, and CBDV - two compounds found naturally in cannabis which aren’t psychoactive like THC – were both successful at reducing nausea in rat subjects.

For the study, researchers “evaluated two phytocannabinoids, cannabidivarin (CBDV) and Δ9 -tetrahydrocannabivarin (THCV) for their ability to produce these behavioural effects characteristic of CB1 receptor inverse agonism in rats.”

In doing so, researchers found that; “THC (2.5 and 10 mg kg-1 ), THCV (10 mg kg-1) and CBDV (200 mg kg-1 ) suppressed LiCl-induced conditioned gaping, suggesting anti-nausea potential.”

The study concludes; “The pattern of findings indicates that neither THCV nor CBDV produced a behavioural profile characteristic of CB1 receptor inverse agonists. As well, these compounds may have therapeutic potential in reducing nausea.”

This study indicates that it may be possible to use THCV or CBDV to help reduce nausea without bringing forth the psychoactive effects associated which THC, which may be seen as undesirable to some.

This research was funded in part by the Natural Sciences and Engineering Research Council of Canada.

Source: TheJointBlog.Com


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Johnny Green


  1. Ok, this is something that was found to be a truth over forty years ago. There are many other useful medical and physical qualities that bear NO harm to the subject making use of such medication/s, [though as any other alternating of the chemical compounds of the physical human body, a very few will have adverse reactions to the change produced…causing various differences in behavior that become far more pronounced.] but much relief where nothing else comes close, without catatonic results to the body and mind.

  2. This is virtually the least surprising news ever, as the anti-nauseant effect of cannabis has been widely known for decades. Ask anyone who’s gone through chemo.
    But always great to have actual science to work with!

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